Do anti-hypertensive drugs act on men and women in the same manner? A team of researchers from Australia report that, vast ranges of treatments for hypertension have same effects, irrespective of the sexes.
Dr. Fiona from Sydney said collective data from 31 previous studies involving 103,268 men and 87,349 women who voluntarily took part in anti-hypertensive treatment trials.
Blood pressure reductions were analogous between the sexes for almost all of the treatment comparisons, the team reports.
Researchers also analyzed that, total of 6,586 strokes, 9,400 cardiovascular events and 3,522 cases of congestive heart failure were recorded during the trials.
On the whole, 41 percent of cardiovascular events and heart failure 32 percent of stroke were observed in women. Death rates with cardiovascular events in both, women and men, were 3.4 percent and 4.4 percent, respectively. Around 40 percent of all causalities occurred in women.
As report mention, both sexes responded fine to blood pressure-lowering agents. “Desired reduction in blood pressures was comparable for men and women in every evaluation made,” the investigators reported.
For the primary results of total main cardiovascular diseases, there was no confirmation that protection level varies in men and women, or that drug regimens belongs to different classes of anti-hypertensive drugs like Angiotensin-Converting Enzyme (ACE) inhibitors, calcium antagonists, diuretics or beta blockers were more effective in one sex than the other.
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